Primary tabs

CEBS Genetic Toxicology: Micronucleus Data

The peripheral blood erythrocyte micronucleus test provides an indication of whether a test article is capable of inducing structural and/or numerical chromosomal damage, specifically micronuclei damage. This data domain contains the frequency of micronucleated erythrocytes (red blood cells) in either bone marrow or peripheral blood in response to exposure to a test article. Examples of endpoints include cell counts, percentages of micronucleated cells, and percentages of immature erythrocytes (polychromatic erythrocytes or PCEs) and mature erythrocytes (normochromatic erythrocytes or NCE) within the total erythrocyte population.
This data domain is part of Chemical Effects in Biological Systems (CEBS) database maintained by the National Toxicology Program.

At the link provided is a PDF and one or more folders containing data. The PDF describes the data, file types, and folder structure present.