The Research and Development Survey (RANDS) is a series of cross-sectional surveys using probability-sampled commercial survey panels. The fifth round of RANDS (RANDS 5) was administered by NORC at the University of Chicago using the AmeriSpeak Panel from January 1, 2022 to March 9, 2022. RANDS 5 contained the embedded probe questions and experiments as in previous rounds of RANDS. It also examined responses to gender identity questions as well as different survey administrations of questions appearing in CDC’s National Intimate Partner and Sexual Violence Survey (NISVS). RANDS 5 has a known survey sampling design and can be used to produce nationally and sub-nationally representative estimates.